منابع مشابه
Ovarian adult stem cells: hope or pitfall?
For many years, ovarian biology has been based on the dogma that oocytes reserve in female mammals included a finite number, established before or at birth and it is determined by the number and quality of primordial follicles developed during the neonatal period. The restricted supply of oocytes in adult female mammals has been disputed in recent years by supporters of postnatal neo-oogenesis....
متن کاملHuman embryonic stem cells: hype or hope?
Embryonic stem (ES) cells have emerged in recent years as powerful tools for the study of in vitro and in vivo development. The engineering of mouse ES cells has been the basis of major advances in mouse transgenesis and subsequent breakthrough findings pertaining to many aspects of development and disease (31) as well as therapeutic targeting (47). Similarly, the recent derivation of human ES ...
متن کاملMesenchymal stem cells in autoimmune diseases: hype or hope?
Intervention with mesenchymal stem cells (MSCs) represents a promising therapeutic tool in treatment-refractory autoimmune diseases. A new report by Schurgers and colleagues in a previous issue of Arthritis Research & Therapy sheds novel mechanistic insight into the pathways employed by MSCs to suppress T-cell proliferation in vitro, but, at the same time, indicates that MSCs do not influence T...
متن کاملAdult Mesenchymal Stem Cells for Tissue Engineering
The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues such as bone marrow and connective tissues has provided exciting prospects for cell-based tissue engineering and regeneration. This review article focuses on the biology of MSCs, their differentiation potentials in vitro and in vivo, and their application in tissue engineering...
متن کاملRegulation of Ovarian Cancer Stem Cells or Tumor-Initiating Cells
Cancer stem cells or tumor-initiating cells (CSC/TICs), which can undergo self-renewal and differentiation, are thought to play critical roles in tumorigenesis, therapy resistance, tumor recurrence and metastasis. Tumor recurrence and chemoresistance are major causes of poor survival rates of ovarian cancer patients, which may be due in part to the existence of CSC/TICs. Therefore, elucidating ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Ovarian Research
سال: 2014
ISSN: 1757-2215
DOI: 10.1186/1757-2215-7-71